B형 간염 예방접종을 맞아도 항체가 안생겨요.

B형 간염 바이러스의 전자 현미경 (TEM) 모습 [Photo and Content Credit: CDC/ E.H. Cook, Jr (www.microbeworld.com) ]

Predictors of non-response to HBV vaccination  (B형 간염 예방접종에 무반응자의 예상조건들)

1. Non-response is defned as an anti-hepatitis B surface antigen (anti-HBs) titre below 10 mIU/mL, typically measured 1–6 months after the last dose of a full immunization schedule.
2. Hyporesponse is defned as an anti-HBs titre greater than 10 and less than 99 mIU/mL.
3. The true non-responder is not protected against HBV infection if exposure occurs.
4. The CDC recommends revaccination of non-responders with one or more additional vaccine doses.
5. In the case of three or more additional booster injections, as many as 30–50% of recipients respond with appropriate production .
6. individuals with risk factors for non-response, some clinicians also advocate using higher doses of vaccine, specifcally 40-mg dosing for the initial three injections instead of the standard adult dosing of 10–20 mg.